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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/32186
Role of JNK in neurodegenerative diseases
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The c-Jun N-terminal kinases (JNK) are members of the MAPK family and can be activated by different stimuli such as cellular stress, heat shock and ultra-violet irradiation. JNKs have different physiological functions and they have been linked to apoptosis in different cell types. Therefore, the JNK signalling pathway is an important target to prevent cell death. In the present chapter, the role of JNKs in neurodegenerative diseases will be discussed, as well as the pharmacological compounds that inhibit this signalling pathway as therapeutic intervention to prevent neuronal death.
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Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32393
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JUNYENT HERENA, Fèlix, et al. Role of JNK in neurodegenerative diseases. Recent Advances in Pharmaceutical Sciences II. 2012. Vol. Editor: Diego Muñoz-Torrero, num. Diego Haro and Joan Vallès, pags. Chapter 2. [consulted: 6 of June of 2026]. Available at: https://hdl.handle.net/2445/32186