Carregant...
Fitxers
Tipus de document
ArticleVersió
Versió publicadaData de publicació
Tots els drets reservats
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/172918
Effectiveness of substituting cyclosporin a with tacrolimus in reducing gingival overgrowth in renal trans-plant patients
Títol de la revista
Director/Tutor
ISSN de la revista
Títol del volum
Recurs relacionat
Resum
Objectives: this study aims to evaluate the effectiveness of periodontal therapy combined with tacrolimus in the suppression of gingival overgrowth (GO) and the effect on GO of changing from cyclosporin A to tacrolimus. Patients and methods: sixteen renal transplant patients, averaging 52 years of age, whose kidney function was stable and were receiving treatment with cyclosporin A, were randomly assigned to one of two groups. In the experimental group, patients were instructed in oral hygiene and underwent periodontal treatment, whereas in the control group, only oral hygiene instructions were given. After the first visit and the change of medication from cyclosporine to tacrolimus in both groups, periodic clinical revisions were carried out for 3 months in order to assess the evolution of GO. Results: all patients showed a progressive decrease in GO. There were no statistically significant differences between the two groups (p>0.05). A greater decrease in GO occurred within the first month after changing the medication. Conclusions: no improved effectiveness in reducing GO was observed for periodontal therapy in combination with tacrolimus. Tacrolimus is an alternative to cyclosporine when attempting to avoid GO in patients with kidney transplants.
Matèries (anglès)
Citació
Citació
PÁRRAGA LINARES, Laura, ALMENDROS-MARQUÉS, Nieves, BERINI AYTÉS, Leonardo, GAY ESCODA, Cosme. Effectiveness of substituting cyclosporin a with tacrolimus in reducing gingival overgrowth in renal trans-plant patients. _Medicina Oral_. Patología Oral y Cirugia Bucal. Vol. 2009, núm. 19, pàgs. 9. [consulta: 25 de febrer de 2026]. ISSN: 1698-4447. [Disponible a: https://hdl.handle.net/2445/172918]