Files

624064.pdf (232.51 KB)

Document type

Article

Version

Accepted version

Publication date

2013-04-25

All rights reserved

Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/108108

Preparation and Double Michael Addition Reactions of a Synthetic Equivalent of Nazarov Reagent

Journal Title

Authors

Director/Tutor

Journal ISSN

Volume Title

Related resource

https://doi.org/10.1021/ol400934c

Abstract

A synthetic equivalent of the Nazarov reagent, the silyl derivative 2, able to undergo base-catalyzed double Michael addition reactions with a,b-unsaturated carbonyl compounds, has been developed. The new reagent satisfactorily reacts with unsaturated indolo[2,3-a]quinolizidine lactams to give pentacyclic yohimbinone-type derivatives.

Subject

Indicadors (Química), Proves i reactius químics, Lactames

Subject (English)

Indicators and test-papers, Chemical tests and reagents, Lactams

Citation

Collections

Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia)
Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)

Citation

AMAT TUSÓN, Mercedes, et al. Preparation and Double Michael Addition Reactions of a Synthetic Equivalent of Nazarov Reagent. Organic Letters. 2013. Vol. 15, num. 10, pags. 2470-2473. ISSN 1523-7060. [consulted: 18 of June of 2026]. Available at: https://hdl.handle.net/2445/108108

Export metadata

JSON - METS

Share record