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cc-by (c) Rubín García, María et al., 2025
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/223387

Sex differences in (poly)phenol intake patterns and cardiovascular risk in Spanish adult population at high risk of cardiovascular disease: Cross-sectional findings

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Background: Men and women tend to follow different dietary patterns, but this is often disregarded when relating diet to health outcomes. Objective: Our aim was to analyze (poly)phenol intake patterns and their association with cardiovascular risk (CVR) according to sex. Methods: 6633 participants were included in this cross-sectional study. The intake of 26 (poly)phenol classes/subclasses was included in the factor analysis obtaining for the total sample, men and women. Linear regression models were performed with the estimation of absolute CVR (Framingham equation) as the dependent variable, and each (poly)phenol pattern categorized into quintiles as the independent variable. Results: For the total sample, (poly)phenol pattern three (olives and olive oil) was positively associated with CVR (βQ5vs.Q1 = 2.71%, 95% CI = 1.45, 3.96), presenting a higher risk of diabetes prevalence, smoking more and consuming more salt. In men, pattern three (olives and olive oil) was also positively associated with CVR (βQ5vs.Q1 = 3.17%, 95% CI = 1.58, 5.64), exhibiting higher prevalence of diabetes and higher sodium intake. Also in men, pattern four (coffee) was positively associated (βQ5vs.Q1 = 1.99 %, 95% CI = 0.26, 3.73) presenting a higher diabetes and current smokers prevalence and higher sugar intake. In women, greater adherence to pattern four (coffee) was associated with higher CVR (βQ5vs.Q1 = 2.19%, 95% CI = 1.05, 3.34). Conclusions: We found sex differences in (poly)phenol intake patterns and in their associations with CVR. These differences may be explained by the fact that subjects at higher risk at baseline may be motivated to improve their dietary habit (reverse causality).

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RUBÍN GARCÍA, María, VITELLI STORELLI, Facundo, TOLEDO ATUCHA, Estefanía, ÁLVAREZ-ÁLVAREZ, Laura, MARTÍNEZ GONZÁLEZ, Miguel ángel, CORELLA PIQUER, Dolores, SALAS SALVADÓ, Jordi, ZOMEÑO, María dolores, MARTÍNEZ, J. alfredo, ALONSO GÓMEZ, Ángel m., WÄRNBERG, Julia, VIOQUE, Jesús, ROMAGUERA, Dora, LÓPEZ MIRANDA, José, ESTRUCH RIBA, Ramon, TINAHONES, Francisco j., SANTOS LOZANO, José manuel, SERRA MAJEM, Lluís, BUENO CAVANILLAS, Aurora, TUR MARÍ, Josep a. (josep antoni), PINTÓ SALA, Xavier, GAFORIO, José juan, MATÍA MARTÍN, Pilar, VIDAL I CORTADA, Josep, MAS-FONTAO, Sebastián, DAIMIEL, Lidia, ROS RAHOLA, Emilio, VÁZQUEZ RUIZ, Zenaida, FERNÁNDEZ DE LA PUENTE, María, ÁLVAREZ-SALA, Andrea, PÉREZ-VEGA, Alejandra, GARCÍA RIOS, Antonio, GONZÁLEZ PALACIOS, Sandra, GÓMEZ-PÉREZ, Ana m., ZULET, María ángeles, CHAPLIN, Alice, CASAS RODRÍGUEZ, Rosa m., CANO IBÁÑEZ, Naomi, TOJAL SIERRA, Lucas, CUETO-GALÁN, Raquel, BUIL COSIALES, Pilar, GUTIÉRREZ-CARRASQUILLA, Liliana, SORLÍ, José v., MALCAMPO, Mireia, ORTIZ-MORALES, Ana m., MIRA-CASTEJÓN, Luis alfredo, RIOS, Santiago, FITÓ COLOMER, Montserrat, MARTÍN SÁNCHEZ, Vicente. Sex differences in (poly)phenol intake patterns and cardiovascular risk in Spanish adult population at high risk of cardiovascular disease: Cross-sectional findings. _Nutrition_. 2025. Vol. 140. [consulta: 15 de gener de 2026]. ISSN: 0899-9007. [Disponible a: https://hdl.handle.net/2445/223387]

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