Document type
ArticleVersion
Published versionPublication date
Publication license
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/157647
Phakillestatins: an underwater unsolved puzzle
Journal Title
Director/Tutor
Journal ISSN
Volume Title
Related resource
Abstract
A critical summary on the discovery of the nineteen members of the phakellistatin family (phakellistatin 1-19), cytotoxic proline‐rich cyclopeptides of marine origin, is reported. Isolation, structural elucidation, and biological properties of the various‐sized natural macrocycles are described, along with the total syntheses and the enigmatic issues of the cytotoxic activity reproducibility.
Subject
Subject (English)
Citation
Citation
MELI, Alessandra, et al. Phakillestatins: an underwater unsolved puzzle. Marine Drugs. 2017. Vol. 15, num. 3, pags. 78. ISSN 1660-3397. [consulted: 13 of June of 2026]. Available at: https://hdl.handle.net/2445/157647