Phakillestatins: an underwater unsolved puzzle
| dc.contributor.author | Meli, Alessandra | |
| dc.contributor.author | Tedesco, Consiglia | |
| dc.contributor.author | Della Sala, Giorgio | |
| dc.contributor.author | Schettini, Rosaria | |
| dc.contributor.author | Albericio Palomera, Fernando | |
| dc.contributor.author | de Riccardis, Francesco | |
| dc.contributor.author | Izzo, Irene | |
| dc.date.accessioned | 2020-04-27T11:59:00Z | |
| dc.date.available | 2020-04-27T11:59:00Z | |
| dc.date.issued | 2017-03-18 | |
| dc.date.updated | 2020-04-27T11:59:00Z | |
| dc.description.abstract | A critical summary on the discovery of the nineteen members of the phakellistatin family (phakellistatin 1-19), cytotoxic proline‐rich cyclopeptides of marine origin, is reported. Isolation, structural elucidation, and biological properties of the various‐sized natural macrocycles are described, along with the total syntheses and the enigmatic issues of the cytotoxic activity reproducibility. | |
| dc.format.extent | 16 p. | |
| dc.format.mimetype | application/pdf | |
| dc.identifier.idgrec | 681090 | |
| dc.identifier.issn | 1660-3397 | |
| dc.identifier.pmid | 28335479 | |
| dc.identifier.uri | https://hdl.handle.net/2445/157647 | |
| dc.language.iso | eng | |
| dc.publisher | MDPI | |
| dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.3390/md15030078 | |
| dc.relation.ispartof | Marine Drugs, 2017, vol. 15, num. 3, p. 78 | |
| dc.relation.projectID | info:eu-repo/grantAgreement/EC/FP7/319011/EU//POMOS | |
| dc.relation.uri | https://doi.org/10.3390/md15030078 | |
| dc.rights | cc-by (c) Meli, Alessandra et al., 2017 | |
| dc.rights.accessRights | info:eu-repo/semantics/openAccess | |
| dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es | |
| dc.source | Articles publicats en revistes (Química Inorgànica i Orgànica) | |
| dc.subject.classification | Aminoàcids | |
| dc.subject.classification | Síntesi de pèptids | |
| dc.subject.classification | Farmacologia | |
| dc.subject.other | Amino acids | |
| dc.subject.other | Peptide synthesis | |
| dc.subject.other | Pharmacology | |
| dc.title | Phakillestatins: an underwater unsolved puzzle | |
| dc.type | info:eu-repo/semantics/article | |
| dc.type | info:eu-repo/semantics/publishedVersion |
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