Derisking Development by a Cocrystallization Screen of a Novel Selective Inhaled JAK-STAT inhibitor

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dc.contributor.authorLlinàs, Antonio
dc.contributor.authorBarbas Cañero, Rafael
dc.contributor.authorFont Bardia, Ma. Mercedes
dc.contributor.authorSmailagic, A.
dc.contributor.authorProhens López, Rafael
dc.date.accessioned2020-05-18T10:34:46Z
dc.date.available2020-10-31T06:10:27Z
dc.date.issued2019-10
dc.date.updated2020-05-18T10:34:46Z
dc.description.abstractThe discovery and detailed characterization of several new solid forms of a novel selective inhaled JAK-STAT inhibitor are described. Using a holistic cocrystallization screen approach to explore its formulation landscape, we decrease the risk of future potential development failures due to a nonoptimal pharmacokinetic lung profile or undesired lung effects in humans.
dc.format.extent35 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idgrec691779
dc.identifier.issn1528-7483
dc.identifier.urihttps://hdl.handle.net/2445/160887
dc.language.isoeng
dc.publisherAmerican Chemical Society
dc.relation.isformatofVersió postprint del document publicat a: https://doi.org/10.1021/acs.cgd.8b01492
dc.relation.ispartofCrystal Growth & Design, 2019, vol. 19, num. 1, p. 403-414
dc.relation.urihttps://doi.org/10.1021/acs.cgd.8b01492
dc.rights(c) American Chemical Society , 2019
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.sourceArticles publicats en revistes (Mineralogia, Petrologia i Geologia Aplicada)
dc.subject.classificationCristal·lografia
dc.subject.classificationSals
dc.subject.otherCrystallography
dc.subject.otherSalts
dc.titleDerisking Development by a Cocrystallization Screen of a Novel Selective Inhaled JAK-STAT inhibitor
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/acceptedVersion

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