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2010-07-15

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cc-by (c) Pérez de Vega, M.J. et al., 2010
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/51423

Solid-Phase Synthesis of New Trp(Nps)-Containing Dipeptide Derivatives as TRPV1 Channel Blockers

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http://dx.doi.org/10.3390/molecules15074924

Abstract

Trp(Nps)-Lys-NH2 derivatives, bearing alkyl or guanidine groups either at the N-terminus or on the Lys side-chain or at both positions were conveniently prepared on solid-phase and evaluated as TRPV1 channel antagonists.

Subject

Síntesi en fase sólida, Canals iònics, Bioquímica, Analgèsics, Ciències de la salut, Proteïnes, Dianes farmacològiques

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Solid-phase synthesis, Ion channels, Biochemistry, Analgesics, Medical sciences, Proteins, Drug targeting

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Articles publicats en revistes (Química Inorgànica i Orgànica)

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PÉREZ DE VEGA, M.J., et al. Solid-Phase Synthesis of New Trp(Nps)-Containing Dipeptide Derivatives as TRPV1 Channel Blockers. Molecules. 2010. Vol. 15, num. 7, pags. 4924-4933. ISSN 1420-3049. [consulted: 9 of June of 2026]. Available at: https://hdl.handle.net/2445/51423

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