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Article

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Published version

Publication date

2024-12-01

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cc-by (c) Selvitella, Silvia et al., 2024
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/220012

Generation of the CTRL EiPS J9 mR6F-8 iPSC line derived from healthy human outgrowth blood endothelial cells (BOECs) using mRNA reprogramming methodology

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https://doi.org/10.1016/j.scr.2024.103606

Abstract

mRNA reprogramming is a technology for generating iPSCs with high efficiency and safety. However, it is not suitable for reprogramming non-adherent cells, the primary cell type in blood. An alternative is to obtain adherent cells from blood for this technology. To validate this approach, we generated a human iPSC line from blood outgrowth endothelial cells (BOECs) using mRNA-based reprogramming. The resulting line, CTRL EiPS J9 mR6F-8, meets iPSC criteria, including an undifferentiated state, pluripotency, genome integrity. This line is available upon request.

Subject

Enginyeria genètica, Endoteli, Cèl·lules

Subject (English)

Genetic engineering, Endothelium, Cells

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Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

Citation

SELVITELLA, Silvia, et al. Generation of the CTRL EiPS J9 mR6F-8 iPSC line derived from healthy human outgrowth blood endothelial cells (BOECs) using mRNA reprogramming methodology. Stem Cell Research. 2024. Vol. 81. ISSN 1876-7753. [consulted: 12 of June of 2026]. Available at: https://hdl.handle.net/2445/220012

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