Generation of the CTRL EiPS J9 mR6F-8 iPSC line derived from healthy human outgrowth blood endothelial cells (BOECs) using mRNA reprogramming methodology

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dc.contributor.authorSelvitella, Silvia
dc.contributor.authorFranco, Marta Pérez
dc.contributor.authorAran, Begoña
dc.contributor.authorVeiga, Anna
dc.contributor.authorKuebler, Bernd
dc.date.accessioned2025-03-25T15:07:36Z
dc.date.available2025-03-25T15:07:36Z
dc.date.issued2024-12-01
dc.date.updated2024-12-10T10:35:35Z
dc.description.abstractmRNA reprogramming is a technology for generating iPSCs with high efficiency and safety. However, it is not suitable for reprogramming non-adherent cells, the primary cell type in blood. An alternative is to obtain adherent cells from blood for this technology. To validate this approach, we generated a human iPSC line from blood outgrowth endothelial cells (BOECs) using mRNA-based reprogramming. The resulting line, CTRL EiPS J9 mR6F-8, meets iPSC criteria, including an undifferentiated state, pluripotency, genome integrity. This line is available upon request.
dc.format.extent5 p.
dc.format.mimetypeapplication/pdf
dc.identifier.issn1876-7753
dc.identifier.pmid39541769
dc.identifier.urihttps://hdl.handle.net/2445/220012
dc.language.isoeng
dc.publisherElsevier BV
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.1016/j.scr.2024.103606
dc.relation.ispartofStem Cell Research, 2024, vol. 81
dc.relation.urihttps://doi.org/10.1016/j.scr.2024.103606
dc.rightscc-by (c) Selvitella, Silvia et al., 2024
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/*
dc.sourceArticles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
dc.subject.classificationEnginyeria genètica
dc.subject.classificationEndoteli
dc.subject.classificationCèl·lules
dc.subject.otherGenetic engineering
dc.subject.otherEndothelium
dc.subject.otherCells
dc.titleGeneration of the CTRL EiPS J9 mR6F-8 iPSC line derived from healthy human outgrowth blood endothelial cells (BOECs) using mRNA reprogramming methodology
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion

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Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))