Misfolded α-Synuclein Assessment in the Skin and CSF by RT-QuIC in Isolated REM Sleep Behavior Disorder

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dc.contributor.authorIranzo, Alex
dc.contributor.authorMammana, Angela
dc.contributor.authorMuñoz Lopetegi, Amaia
dc.contributor.authorDellavalle, Sofia
dc.contributor.authorMayà Casalprim, Gerard
dc.contributor.authorRossi, Marcello
dc.contributor.authorSerradell, Mónica
dc.contributor.authorBaiardi, Simone
dc.contributor.authorArqueros, Aurora
dc.contributor.authorQuadalti, Corinne
dc.contributor.authorPerissinotti, Andrés
dc.contributor.authorRuggeri, Edoardo
dc.contributor.authorSantamaria Cano, Joan
dc.contributor.authorGaig Ventura, Carles
dc.contributor.authorParchi, Piero
dc.date.accessioned2025-04-03T10:46:20Z
dc.date.available2025-04-03T10:46:20Z
dc.date.issued2023-05-02
dc.date.updated2025-04-03T10:46:20Z
dc.description.abstractReal-time quaking-induced conversion (RT-QuIC) assay detects misfolded α-synuclein (AS) in the skin and CSF of patients with the synucleinopathies Parkinson disease and dementia with Lewy bodies. Isolated REM sleep behavior disorder (IRBD) constitutes the prodromal stage of these synucleinopathies. We aimed to compare the ability of RT-QuIC to identify AS in the skin and CSF of patients with IRBD.
dc.format.extent11 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idgrec756164
dc.identifier.issn0028-3878
dc.identifier.pmid36931726
dc.identifier.urihttps://hdl.handle.net/2445/220233
dc.language.isoeng
dc.publisherLippincott, Williams & Wilkins. Wolters Kluwer Health
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.1212/WNL.0000000000207147
dc.relation.ispartofNeurology, 2023, vol. 100, num.18, p. E1944-E1954
dc.relation.urihttps://doi.org/10.1212/WNL.0000000000207147
dc.rights(c) American Academy of Neurology, 2023
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.sourceArticles publicats en revistes (Medicina)
dc.subject.classificationTrastorns del son
dc.subject.classificationDemència amb cossos de Lewy
dc.subject.classificationMalaltia de Parkinson
dc.subject.otherSleep disorders
dc.subject.otherLewy body dementia
dc.subject.otherParkinson's disease
dc.titleMisfolded α-Synuclein Assessment in the Skin and CSF by RT-QuIC in Isolated REM Sleep Behavior Disorder
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion

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