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2022-09-30

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Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/191069

Clostridioides difficile infection recurrence in the VINCat hospitals: a prospective observational cohort study

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Recurs relacionat

https://doi.org/10.2217/fmb-2022-0076

Resum

Background: The 2016 cumulative incidence of Clostridioides difficile infection (CDI) in Spain was reported by the European Center for Disease Control to be above the mean of other European countries. The aim of this multicenter prospective observational cohort study was to examine the risk factors that determine 90-day CDI recurrence in Catalonia, Spain. Methods: The study included 558 consecutive adults admitted to hospital who had a symptomatic, first positive CDI diagnosis. Sociodemographic, clinical and epidemiological variables were recorded. The primary outcome was 90-day CDI recurrence. Results: In this Catalan population, having received more than one course of antibiotics in the 30 days prior to CDI diagnosis (odds ratio: 2.459; 95% CI: 1.195-5.060; p = 0.015) and active chemotherapy (odds ratio: 4.859; 95% CI: 1.495-15.792; p = 0.009) are significant predictors of 90-day CDI recurrence. Conclusion: The identification of independent risk factors of 90-day CDI recurrence will enable the optimization of preventive measures in at-risk populations.

Matèries

Colitis, Antibiòtics, Efectes secundaris dels medicaments, Higiene hospitalària

Matèries (anglès)

Colitis, Antibiotics, Drug side effects, Hospital hygiene

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Col·leccions

Articles publicats en revistes (Infermeria de Salut Pública, Salut mental i Maternoinfantil)
Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

Citació

PUJOL ROJO, Miquel, LIMÓN, Enrique, SOPENA, Nieves, LÓPEZ-CONTRERAS, Joaquín, CASTELLÀ, Laia, CUQUET, Jordi, LÓPEZ-SÁNCHEZ, Maria, PÉREZ, Rafel, GUDIOL GONZÁLEZ, Carlota, COLOMA, Ana, MARIMÓN, Mariló, ESPINACH, Joan, ANDRES, Marta, MARTOS, Purificación, HERNÁNDEZ, Sergi, ALMENDRAL, Alexander, SALIBA, Patrick, CARVALHO RODRIGUES, Gonçalo, CALBO, Esther. Clostridioides difficile infection recurrence in the VINCat hospitals: a prospective observational cohort study. _Future Microbiology_. 2022. Vol. 17, núm. 1445-1453. [consulta: 14 de gener de 2026]. ISSN: 1746-0913. [Disponible a: https://hdl.handle.net/2445/191069]

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