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Accepted version

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2018-01

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cc-by-nc-nd (c) Elsevier B.V., 2018
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/132145

The effect of pulmonary surfactant on the in vitro activity of Iclaprim against common respiratory bacterial pathogens

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https://doi.org/10.1016/j.diagmicrobio.2017.09.011

Abstract

The in vitro antimicrobial activity of iclaprim, a novel diaminopyrimidine, against common respiratory bacteria remained unchanged in the presence of pulmonary surfactant (Survanta®) at concentrations that greatly antagonized the antimicrobial activity of daptomycin. These results indicate that iclaprim could be a potential treatment for pneumonia caused by susceptible and multidrug resistant bacteria.

Subject

Pneumònia, Bacteris patògens, Efecte dels medicaments sobre els microorganismes

Subject (English)

Pneumonia, Pathogenic bacteria, Effect of drugs on microorganisms

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Articles publicats en revistes (Medicina)
Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)

Citation

HUANG, David B., et al. The effect of pulmonary surfactant on the in vitro activity of Iclaprim against common respiratory bacterial pathogens. Diagnostic Microbiology and Infectious Disease. 2018. Vol. 90, num. 1, pags. 64-66. ISSN 0732-8893. [consulted: 17 of August of 2026]. Available at: https://hdl.handle.net/2445/132145

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