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Iron oxide nanoparticles for magnetically guided and magnetically responsive drug delivery
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In this review, we discuss the recent advances in and problems with the use of magnetically-guided and magnetically-responsive nanoparticles in drug delivery and magnetofection. In magnetically-guided nanoparticles, a constant external magnetic field is used to transport magnetic nanoparticles loaded with drugs to a specific site within the body or to increase the transfection capacity. Magnetofection is the delivery of nucleic acids under the influence of a magnetic field acting on nucleic acid vectors that are associated with magnetic nanoparticles. In magnetically-responsive nanoparticles, magnetic nanoparticles are encapsulated or embedded in a larger colloidal structure that carries a drug. In this last case, an alternating magnetic field can modify the structure of the colloid, thereby providing spatial and temporal control over drug release.
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ESTELRICH I LATRÀS, Joan, et al. Iron oxide nanoparticles for magnetically guided and magnetically responsive drug delivery. International Journal of Molecular Sciences. 2015. Vol. 16, num. 4, pags. 8070-8101. ISSN 1661-6596. [consulted: 11 of August of 2026]. Available at: https://hdl.handle.net/2445/149424