Iron oxide nanoparticles for magnetically guided and magnetically responsive drug delivery

dc.contributor.authorEstelrich i Latràs, Joan
dc.contributor.authorEscribano Ferrer, Elvira
dc.contributor.authorQueralt i Regué, Josep
dc.contributor.authorBusquets i Viñas, Ma. Antonia
dc.date.accessioned2020-02-06T10:22:53Z
dc.date.available2020-02-06T10:22:53Z
dc.date.issued2015-04-10
dc.date.updated2020-02-06T10:22:54Z
dc.description.abstractIn this review, we discuss the recent advances in and problems with the use of magnetically-guided and magnetically-responsive nanoparticles in drug delivery and magnetofection. In magnetically-guided nanoparticles, a constant external magnetic field is used to transport magnetic nanoparticles loaded with drugs to a specific site within the body or to increase the transfection capacity. Magnetofection is the delivery of nucleic acids under the influence of a magnetic field acting on nucleic acid vectors that are associated with magnetic nanoparticles. In magnetically-responsive nanoparticles, magnetic nanoparticles are encapsulated or embedded in a larger colloidal structure that carries a drug. In this last case, an alternating magnetic field can modify the structure of the colloid, thereby providing spatial and temporal control over drug release.
dc.format.extent32 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idgrec649194
dc.identifier.issn1661-6596
dc.identifier.pmid25867479
dc.identifier.urihttps://hdl.handle.net/2445/149424
dc.language.isoeng
dc.publisherMDPI
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.3390/ijms16048070
dc.relation.ispartofInternational Journal of Molecular Sciences, 2015, vol. 16, num. 4, p. 8070-8101
dc.relation.urihttps://doi.org/10.3390/ijms16048070
dc.rightscc-by (c) Estelrich i Latràs, Joan et al., 2015
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es
dc.sourceArticles publicats en revistes (Farmàcia, Tecnologia Farmacèutica i Fisicoquímica)
dc.subject.classificationNanopartícules
dc.subject.classificationLiposomes
dc.subject.classificationQuimioteràpia
dc.subject.classificationÒxid de ferro
dc.subject.otherNanoparticles
dc.subject.otherLiposomes
dc.subject.otherChemotherapy
dc.subject.otherFerric oxide
dc.titleIron oxide nanoparticles for magnetically guided and magnetically responsive drug delivery
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion

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