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Article

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Accepted version

Publication date

2019-03-19

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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/132634

Stereoselective synthesis of protected peptides containing an anti β‐Hydroxy tyrosine

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Related resource

https://doi.org/10.1002/ejoc.201900301

Abstract

Protected peptides containing an anti b-hydroxy tyrosine are synthesized in a straightforward and highly efficient manner through the direct and stereoselective addition of N-azidoacetyl-4-isopropyl-1,3-thiazolidine-2-thione to dialkyl acetals catalyzed by a nickel(II) complex, the forging of an amide bond by removal of the chiral auxiliary with an amino ester, and final coupling with a third amino acid.

Subject

Pèptids, Estereoquímica, Quiralitat

Subject (English)

Peptides, Stereochemistry, Chirality

Citation

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Articles publicats en revistes (Química Inorgànica i Orgànica)

Citation

FERNANDEZ-VALPARIS, Javier, ROMEA, Pedro and URPÍ TUBELLA, Fèlix. Stereoselective synthesis of protected peptides containing an anti β‐Hydroxy tyrosine. European Journal of Organic Chemistry. 2019. Vol. 2019, num. 16, pags. 2745-2752. ISSN 1434-193X. [consulted: 14 of August of 2026]. Available at: https://hdl.handle.net/2445/132634

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