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Stereoselective synthesis of protected peptides containing an anti β‐Hydroxy tyrosine

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dc.contributor.authorFernandez-Valparis, Javier
dc.contributor.authorRomea, Pedro
dc.contributor.authorUrpí Tubella, Fèlix
dc.date.accessioned2019-05-03T11:22:00Z
dc.date.available2020-03-19T06:10:15Z
dc.date.issued2019-03-19
dc.date.updated2019-05-03T11:22:00Z
dc.description.abstractProtected peptides containing an anti b-hydroxy tyrosine are synthesized in a straightforward and highly efficient manner through the direct and stereoselective addition of N-azidoacetyl-4-isopropyl-1,3-thiazolidine-2-thione to dialkyl acetals catalyzed by a nickel(II) complex, the forging of an amide bond by removal of the chiral auxiliary with an amino ester, and final coupling with a third amino acid.
dc.format.extent8 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idgrec689924
dc.identifier.issn1434-193X
dc.identifier.urihttps://hdl.handle.net/2445/132634
dc.language.isoeng
dc.publisherWiley-VCH
dc.relation.isformatofVersió postprint del document publicat a: https://doi.org/10.1002/ejoc.201900301
dc.relation.ispartofEuropean Journal of Organic Chemistry, 2019, vol. 2019, num. 16, p. 2745-2752
dc.relation.urihttps://doi.org/10.1002/ejoc.201900301
dc.rights(c) Wiley-VCH, 2019
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.sourceArticles publicats en revistes (Química Inorgànica i Orgànica)
dc.subject.classificationPèptids
dc.subject.classificationEstereoquímica
dc.subject.classificationQuiralitat
dc.subject.otherPeptides
dc.subject.otherStereochemistry
dc.subject.otherChirality
dc.titleStereoselective synthesis of protected peptides containing an anti β‐Hydroxy tyrosine
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/acceptedVersion

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