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Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/107496
The longitudinal association between a discrepancy measure of anosognosia in patients with dementia, caregiver burden and depression
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Background: According to cross-sectional studies, there is an association between anosognosia in people with dementia and caregiver's burden and depression. Anosognosia in patients may be a cause of caregiver burden and depression. However, variability in caregiver anosognosia ratings may exist as caregivers with burden and depression may have a more pessimistic view of the patients' health. Objective: to assess the variability of caregiver anosognosia ratings of patients with dementia using a widely used anosognosia scale and its longitudinal relationship with caregiver burden and depression. Methods: A convenience cohort of 221 consecutive dementia outpatient and caregiver dyads was followed up at 12 and 24 months. The main instruments used were the Anosognosia Questionnaire-Dementia (AQ-D), Caregiver Burden Interview, and Geriatric Depression Scale. Linear mixed models were used including time as a factor in every model. Multivariate analyses controlled for caregiver's socio-demographic and possible confounding factors. Results: Attrition at 12 and 24 months was 24.9% and 42.5% respectively. Patients at baseline were on average 77.8 years of age, 63.3% were women, and 63.3% had <5 years of education. In the bivariate analyses, caregiver burden, depression, and gender were associated with caregiver ratings of total, cognitive, and personality AQ-D of the patient at different time points. Multivariate analyses revealed burden as the caregiver variable most consistently associated with total, cognitive, and personality caregiver AQ-D ratings of the patient. Conclusion: Some caregiver characteristics, especially burden, are associated with caregiver ratings of AQ-D with regard to the patient.
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PERALES-PUCHALT, Jaime, TURRÓ-GARRIGA, Oriol, GASCÓN-BAYARRI, Jordi, REÑÉ RAMÍREZ, Ramon, CONDE SALA, Josep lluís. The longitudinal association between a discrepancy measure of anosognosia in patients with dementia, caregiver burden and depression. _Journal of Alzheimer's Disease_. 2016. Vol. 53, núm. 3, pàgs. 1133-1143. [consulta: 25 de febrer de 2026]. ISSN: 1387-2877. [Disponible a: https://hdl.handle.net/2445/107496]