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2024-01-01

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cc-by-nc-nd (c) Camps Font, Octavi et al., 2024
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/217417

Antibiotic prophylaxis in the prevention of dry socket and surgical site infection after lower third molar extraction: a network meta-analysis.

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Recurs relacionat

https://doi.org/10.1016/j.ijom.2023.08.001

Resum

Clinicians frequently prescribe systemic antibiotics after lower third molar extractions to prevent complications such as surgical site infections and dry socket. A systematic review of randomised clinical trials was conducted to compare the risk of dry socket and surgical site infection after the removal of lower third molars with different prophylactic antibiotics. The occurrence of any antibiotic-related adverse event was also analysed. A pairwise and network meta-analysis was performed to establish direct and indirect comparisons of each outcome variable. Sixteen articles involving 2158 patients (2428 lower third molars) were included, and the following antibiotics were analysed: amoxicillin (with and without clavulanic acid), metronidazole, azithromycin, and clindamycin. Pooled results favoured the use of antibiotics to reduce dry socket and surgical site infection after the removal of a lower third molar, with a number needed to treat of 25 and 18, respectively. Although antibiotic prophylaxis was found to significantly reduce the risk of dry socket and surgical site infection in patients undergoing lower third molar extraction, the number of patients needed to treat was high. Thus, clinicians should evaluate the need to prescribe antibiotics taking into consideration the patient's systemic status and the individual risk of developing a postoperative infection.

Matèries

Efectes secundaris dels medicaments, Extracció dental, Dent molar, Infeccions quirúrgiques, Antibiòtics

Matèries (anglès)

Drug side effects, Teeth extraction, Molar, Surgical wound infection, Antibiotics

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Articles publicats en revistes (Medicina)
Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

Citació

CAMPS FONT, Octavi, SÁBADO BUNDÓ, Helena, TOLEDANO SERRABONA, Jorge, VALMASEDA-DE-LA-ROSA, Núria, BARBOSA DE FIGUEIREDO, Rui pedro, VALMASEDA CASTELLÓN, Eduardo. Antibiotic prophylaxis in the prevention of dry socket and surgical site infection after lower third molar extraction: a network meta-analysis.. _International Journal of Oral and Maxillofacial Surgery_. 2024. Vol. 53, núm. 1, pàgs. 57-67. [consulta: 30 de gener de 2026]. ISSN: 0901-5027. [Disponible a: https://hdl.handle.net/2445/217417]

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