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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/128986
Glial and neuronal markers in cerebrospinal fluid in different types of multiple sclerosis
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Abstract
In the present study, CSF concentrations of NFL, t-tau, p-tau, GFAP, S-100B, YKL-40, MCP-1, alpha-sAPP, beta-sAPP, and A beta 38, A beta 40, A beta 42 were measured in 324 MS patients to test whether a correlation among the biomarkers exists and whether the profile of CSF biomarkers varies among the different types of MS. The CSF concentrations of NFL were significantly higher in RRMS while CSF concentrations of GFAP were higher in PPMS. CSF concentrations of NFL correlated with YKL-40 in CIS patients while CSF concentrations of GFAP correlated with YKL-40 in RRMS patients.
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MAÑÉ MARTÍNEZ, M. Alba, et al. Glial and neuronal markers in cerebrospinal fluid in different types of multiple sclerosis. Journal of Neuroimmunology. 2016. Vol. 299, num. 112-117. ISSN 0165-5728. [consulted: 16 of August of 2026]. Available at: https://hdl.handle.net/2445/128986