Glial and neuronal markers in cerebrospinal fluid in different types of multiple sclerosis

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dc.contributor.authorMañé Martínez, M. Alba
dc.contributor.authorOlsson, Bob
dc.contributor.authorBau, Laura
dc.contributor.authorMatas Martín, Elisabet
dc.contributor.authorCobo Calvo, Álvaro
dc.contributor.authorAndreasson, Ulf
dc.contributor.authorBlennow, Kaj
dc.contributor.authorRomero Pinel, Lucía María
dc.contributor.authorMartínez Yélamos, Sergio
dc.contributor.authorZetterberg, Henrik
dc.date.accessioned2019-02-27T11:09:39Z
dc.date.available2019-02-27T11:09:39Z
dc.date.issued2016-10-15
dc.date.updated2019-02-27T11:09:39Z
dc.description.abstractIn the present study, CSF concentrations of NFL, t-tau, p-tau, GFAP, S-100B, YKL-40, MCP-1, alpha-sAPP, beta-sAPP, and A beta 38, A beta 40, A beta 42 were measured in 324 MS patients to test whether a correlation among the biomarkers exists and whether the profile of CSF biomarkers varies among the different types of MS. The CSF concentrations of NFL were significantly higher in RRMS while CSF concentrations of GFAP were higher in PPMS. CSF concentrations of NFL correlated with YKL-40 in CIS patients while CSF concentrations of GFAP correlated with YKL-40 in RRMS patients.
dc.format.extent6 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idgrec676754
dc.identifier.issn0165-5728
dc.identifier.pmid27725108
dc.identifier.urihttps://hdl.handle.net/2445/128986
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.isformatofVersió postprint del document publicat a: https://doi.org/10.1016/j.jneuroim.2016.08.004
dc.relation.ispartofJournal of Neuroimmunology, 2016, vol. 299, p. 112-117
dc.relation.urihttps://doi.org/10.1016/j.jneuroim.2016.08.004
dc.rightscc-by-nc-nd (c) Elsevier B.V., 2016
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es
dc.sourceArticles publicats en revistes (Ciències Clíniques)
dc.subject.classificationEsclerosi múltiple
dc.subject.classificationMarcadors bioquímics
dc.subject.otherMultiple sclerosis
dc.subject.otherBiochemical markers
dc.titleGlial and neuronal markers in cerebrospinal fluid in different types of multiple sclerosis
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/acceptedVersion

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