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2019-01-01

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Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/171919

Cutaneous, genital and oral lichen planus: a descriptive study of 274 patients

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https://doi.org/10.4317/medoral.22656

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Background: Lichen planus (LP) is a chronic autoimmune disease that affects the oral mucosa as well as the skin, genital mucosa and other sites. Objective: to evaluate the correlation between oral, genital and cutaneous lichen planus, in a sample of LP patients. Material and methods: This descriptive study reviewed 274 clinical histories of patients, who all presented histological confirmation of lichen planus verified by a pathologist, attending research centers in Barcelona. Results: A total of 40 LP patients (14.59%) presented genital lesions. Of 131 patients with cutaneous LP (47.8%), the most commonly affected zones were the body's flexor surfaces, representing 60.1% of cases. 24% of patients (n=55) related the start of the lesions with previous stress events. Of the 131 subjects with cutaneous lesions, 19% (n=25) also presented oral lichen planus (OLP). Of the total sample, 53.6% (n=147) of patients presented oral lesions. The systemic diseases most commonly associated with this patient sample were psychological problems such as stress, anxiety and depression (48%), hypertension (27%), gastric problems (12%), and diabetes (9.7%). A family history of lichen planus was found in only 2 cases (0,72%) out of the total of 274. Conclusions: Any patient with OLP should undergo a thorough history and examination to investigate potential extraoral manifestations. The fact that 37 patients with OLP in this patient series were identified with simultaneous involvement at more than one site highlights the need for thorough evaluation and multidisciplinary approaches to this disease.

Matèries

Liquen pla, Manifestacions orals de les malalties, Aparell genital

Matèries (anglès)

Lichen planus, Oral manifestations of general diseases, Generative organs

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Articles publicats en revistes (Odontoestomatologia)
Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

Citació

CASSOL SPANEMBERG, Juliana, BLANCO CARRIÓN, Andrés, RODRÍGUEZ DE RIVERA CAMPILLO, Ma eugenia, ESTRUGO DEVESA, Albert, JANÉ SALAS, Enric, LÓPEZ LÓPEZ, José. Cutaneous, genital and oral lichen planus: a descriptive study of 274 patients. _Medicina Oral_. Patología Oral y Cirugía Bucal. Vol.  2019, núm. 24, pàgs. 1. [consulta: 20 de gener de 2026]. ISSN: 1698-4447. [Disponible a: https://hdl.handle.net/2445/171919]

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