Modified siRNAs for the study of the PAZ domain

dc.contributor.authorSomoza, Álvaro
dc.contributor.authorTerrazas Martínez, Montserrat
dc.contributor.authorEritja i Casadellà, Ramon
dc.date.accessioned2021-08-31T11:41:03Z
dc.date.available2021-08-31T11:41:03Z
dc.date.issued2010-05-19
dc.date.updated2021-08-31T11:41:03Z
dc.description.abstractChemical modifications aimed at stabilizing the interaction between the 3'-end of siRNAs and the PAZ domain of RISC have been tested for their effect on RNAi activity. Such modifications contribute positively to the stability of siRNAs in human serum.
dc.format.extent3 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idgrec713433
dc.identifier.issn1359-7345
dc.identifier.urihttps://hdl.handle.net/2445/179784
dc.language.isoeng
dc.publisherRoyal Society of Chemistry
dc.relation.isformatofVersió postprint del document publicat a: https://doi.org/10.1039/C003221B
dc.relation.ispartofChemical Communications, 2010, vol. 46, p. 4270-4272
dc.relation.urihttps://doi.org/10.1039/C003221B
dc.rights(c) Somoza, Álvaro et al., 2010
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.sourceArticles publicats en revistes (Química Inorgànica i Orgànica)
dc.subject.classificationRNA
dc.subject.classificationFixació de proteïnes
dc.subject.classificationModificació química de les proteïnes
dc.subject.otherRNA
dc.subject.otherProtein binding
dc.subject.otherChemical modification of proteins
dc.titleModified siRNAs for the study of the PAZ domain
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/acceptedVersion

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