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cc by-nc (c) Beedle, Amy EM. et al., 2023
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/201872

The reversibility of cellular mechano-activation

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The cellular microenvironment is highly heterogeneous and dynamic. Therefore, cells must be equipped with molecular tools to adapt and respond to constantly fluctuating inputs. One such input is mechanical force, which activates signalling and regulates cell behaviour in the process of mechanotransduction. Whereas the mechanisms activating mechanotransduction are well studied, the reversibility of this process, whereby cells disassemble and reverse force-activated signalling pathways upon cessation of mechanical stimulation is far less understood. In this review we will outline some of the key experimental techniques to investigate the reversibility of mechanical signalling, and key discoveries arising from them.Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.

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Beedle AE;Roca-Cusachs P. The reversibility of cellular mechano-activation. Current Opinion In Cell Biology, 2023, 84, 102229-NA

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BEEDLE, Amy e. m., ROCA-CUSACHS SOULERE, Pere. The reversibility of cellular mechano-activation. _Current Opinion In Cell Biology_. 2023. Vol. 84. [consulta: 30 de gener de 2026]. ISSN: 1879-0410. [Disponible a: https://hdl.handle.net/2445/201872]

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