The reversibility of cellular mechano-activation

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dc.contributor.authorBeedle, Amy E. M.
dc.contributor.authorRoca-Cusachs Soulere, Pere
dc.date.accessioned2023-09-13T10:37:43Z
dc.date.available2023-09-13T10:37:43Z
dc.date.issued2023-10-01
dc.date.updated2023-09-06T06:31:08Z
dc.description.abstractThe cellular microenvironment is highly heterogeneous and dynamic. Therefore, cells must be equipped with molecular tools to adapt and respond to constantly fluctuating inputs. One such input is mechanical force, which activates signalling and regulates cell behaviour in the process of mechanotransduction. Whereas the mechanisms activating mechanotransduction are well studied, the reversibility of this process, whereby cells disassemble and reverse force-activated signalling pathways upon cessation of mechanical stimulation is far less understood. In this review we will outline some of the key experimental techniques to investigate the reversibility of mechanical signalling, and key discoveries arising from them.Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.
dc.format.extent6 p.
dc.format.mimetypeapplication/pdf
dc.identifier.citationBeedle AE;Roca-Cusachs P. The reversibility of cellular mechano-activation. Current Opinion In Cell Biology, 2023, 84, 102229-NA
dc.identifier.idimarina6601987
dc.identifier.issn1879-0410
dc.identifier.pmid37633090
dc.identifier.urihttps://hdl.handle.net/2445/201872
dc.language.isoeng
dc.publisherElsevier BV
dc.relation.isformatofhttps://doi.org/10.1016/j.ceb.2023.102229
dc.relation.ispartofCurrent Opinion In Cell Biology, 2023, vol. 84
dc.relation.urihttps://doi.org/10.1016/j.ceb.2023.102229
dc.rightscc by-nc (c) Beedle, Amy EM. et al., 2023
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by-nc/3.0/es/*
dc.sourceArticles publicats en revistes (Institut de Bioenginyeria de Catalunya (IBEC))
dc.subject.classificationTransducció de senyal cel·lular
dc.subject.classificationFisiologia cel·lular
dc.subject.otherCellular signal transduction
dc.subject.otherCell physiology
dc.titleThe reversibility of cellular mechano-activation
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion

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