Metachronous colorectal cancer risks after extended or segmental resection in MLH1, MSH2, and MSH6 Lynch syndrome: multicentre study from the Prospective Lynch Syndrome Database

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dc.contributor.authorProspective Lynch Syndrome Database
dc.contributor.authorCapella, Gabriel
dc.contributor.authorPineda Riu, Marta
dc.contributor.authorDueñas, Nuria
dc.contributor.authorBrunet, Joan
dc.date.accessioned2025-07-08T10:35:54Z
dc.date.available2025-07-08T10:35:54Z
dc.date.issued2025-03-28
dc.date.updated2025-06-19T15:00:48Z
dc.description.abstractThis first prospective observational study evaluates the impact of extended versus segmental colorectal surgery on the risk of metachronous colorectal cancer (CRC) in patients with Lynch syndrome, analyzing data from the Prospective Lynch Syndrome Database version 5. Extended resection significantly reduced the risk of metachronous CRC in path_MLH1, path_MSH2, and path_MSH6 carriers compared to segmental resection.
dc.format.extent11 p.
dc.format.mimetypeapplication/pdf
dc.identifier.issn1365-2168
dc.identifier.pmid40231433
dc.identifier.urihttps://hdl.handle.net/2445/222101
dc.language.isoeng
dc.publisherOxford University Press (OUP)
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.1093/bjs/znaf061
dc.relation.ispartofBritish journal of surgery, 2025, vol. 112, num. 4
dc.relation.urihttps://doi.org/10.1093/bjs/znaf061
dc.rightscc by (c) Prospective Lynch Syndrome Database, 2025
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/*
dc.sourceArticles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
dc.subject.classificationCirurgia colorectal
dc.subject.classificationCàncer colorectal
dc.subject.otherColorectal cancer
dc.subject.otherColorectal surgery
dc.titleMetachronous colorectal cancer risks after extended or segmental resection in MLH1, MSH2, and MSH6 Lynch syndrome: multicentre study from the Prospective Lynch Syndrome Database
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion

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