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cc-by-nc-nd (c) De Prisco, Michele et al., 2022
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/195849

Defining clinical characteristics of emotion dysregulation in bipolar disorder: A systematic review and meta-analysis

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Emotion dysregulation (ED) is characterized by rigid and frequent use of maladaptive emotion regulation (ER) strategies. Conceptualized as a transdiagnostic feature, ED may occur in both clinical and non-clinical populations, including people diagnosed with bipolar disorder (BD) and their first-degree relatives (FDRs), though expected to manifest with differential clinical features. To this end, we conducted a systematic review and meta-analysis of the literature comparing people with BD to healthy controls (HCs) or FDRs, from inception up to November 25, 2021, across major databases. Random-effects meta-analyses considered twenty-eight studies assessing ER/ED with a validated scale. Patients with BD differed from HCs in adopting more maladaptive ER strategies, such as rumination, risk-taking behaviors, negative focus, and less adaptive ones. Unaffected FDRs differed from people with BD, yet to a lower extent, suggesting that ED may span a continuum. ED in BD should be widely explored to better understand its course and management, with specific interventions aimed at reducing its burden on both high-risk and full-threshold populations.

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DE PRISCO, Michele, OLIVA, Vincenzo, FICO, Giovanna, FORNARO, Michele, DE BARTOLOMEIS, Andrea, SERRETTI, Alessandro, VIETA I PASCUAL, Eduard, MURRU, Andrea. Defining clinical characteristics of emotion dysregulation in bipolar disorder: A systematic review and meta-analysis. _Neuroscience and Biobehavioral Reviews_. 2022. Vol. 142, núm. 104914. [consulta: 15 de gener de 2026]. ISSN: 0149-7634. [Disponible a: https://hdl.handle.net/2445/195849]

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