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2022-11-01

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cc-by-nc-nd (c) De Prisco, Michele et al., 2022
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/195849

Defining clinical characteristics of emotion dysregulation in bipolar disorder: A systematic review and meta-analysis

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https://doi.org/10.1016/j.neubiorev.2022.104914

Abstract

Emotion dysregulation (ED) is characterized by rigid and frequent use of maladaptive emotion regulation (ER) strategies. Conceptualized as a transdiagnostic feature, ED may occur in both clinical and non-clinical populations, including people diagnosed with bipolar disorder (BD) and their first-degree relatives (FDRs), though expected to manifest with differential clinical features. To this end, we conducted a systematic review and meta-analysis of the literature comparing people with BD to healthy controls (HCs) or FDRs, from inception up to November 25, 2021, across major databases. Random-effects meta-analyses considered twenty-eight studies assessing ER/ED with a validated scale. Patients with BD differed from HCs in adopting more maladaptive ER strategies, such as rumination, risk-taking behaviors, negative focus, and less adaptive ones. Unaffected FDRs differed from people with BD, yet to a lower extent, suggesting that ED may span a continuum. ED in BD should be widely explored to better understand its course and management, with specific interventions aimed at reducing its burden on both high-risk and full-threshold populations.

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Trastorn bipolar, Trastorns afectius, Emocions, Metaanàlisi, Adaptació (Psicologia)

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Manic-depressive illness, Affective disorders, Emotions, Meta-analysis, Adaptability (Psychology)

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Articles publicats en revistes (Medicina)
Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)

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DE PRISCO, Michele, et al. Defining clinical characteristics of emotion dysregulation in bipolar disorder: A systematic review and meta-analysis. Neuroscience and Biobehavioral Reviews. 2022. Vol. 142, num. 104914. ISSN 0149-7634. [consulted: 14 of August of 2026]. Available at: https://hdl.handle.net/2445/195849

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