Evidence of association of the NLRP1 gene with giant cell arteritis

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dc.contributor.authorSerrano, Aurora
dc.contributor.authorCarmona, F. David
dc.contributor.authorCastañeda, Santos
dc.contributor.authorSolans, Roser
dc.contributor.authorHernández Rodríguez, José
dc.contributor.authorCid Xutglà, M. Cinta
dc.contributor.authorPrieto González, Sergio
dc.contributor.authorMiranda-Filloy, José A.
dc.contributor.authorRodríguez-Rodríguez, Luis
dc.contributor.authorMorado, Inmaculada C.
dc.contributor.authorGómez Vaquero, Carmen
dc.contributor.authorBlanco, Ricardo
dc.contributor.authorSopeña, Bernardo
dc.contributor.authorOrtego Centeno, Norberto
dc.contributor.authorUnzurrunzaga, Ainhoa
dc.contributor.authorMarí-Alfonso, Begoña
dc.contributor.authorSánchez-Martin, Julio
dc.contributor.authorGarcía-Villanueva, María Jesús
dc.contributor.authorHidalgo-Conde, Ana
dc.contributor.authorPazzola, Giulia
dc.contributor.authorBoiardi, Luigi
dc.contributor.authorSalvarani, Carlo
dc.contributor.authorGonzález-Gay, Miguel A.
dc.contributor.authorMartín, Javier
dc.date.accessioned2017-06-19T10:24:29Z
dc.date.available2017-06-19T10:24:29Z
dc.date.issued2013-04
dc.date.updated2017-06-19T10:24:29Z
dc.description.abstractRecent studies have focused attention on the involvement of NLRP1 to confer susceptibility for extended autoimmune/inflammatory disorders, being considered a common risk factor in autoimmunity. NLRP1 provides a scaffold for the assembly of the inflammasome that activates caspases 1 and 5, required for processing and activation of the proinflammatory cytokines interleukin 1β (IL-1β), IL-18 and IL-33 and promoting inflammation.
dc.format.extent3 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idgrec641076
dc.identifier.issn0003-4967
dc.identifier.pmid23253924
dc.identifier.urihttps://hdl.handle.net/2445/112543
dc.language.isoeng
dc.publisherBMJ Publishing Group
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.1136/annrheumdis-2012-202609
dc.relation.ispartofAnnals of the Rheumatic Diseases, 2013, vol. 72, num. 4, p. 628-630
dc.relation.urihttps://doi.org/10.1136/annrheumdis-2012-202609
dc.rights(c) BMJ Publishing Group, 2013
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.sourceArticles publicats en revistes (Ciències Clíniques)
dc.subject.classificationArteritis de cèl·lules gegants
dc.subject.classificationPolimorfisme genètic
dc.subject.classificationGenètica
dc.subject.otherGiant cell arteritis
dc.subject.otherGenetic polymorphisms
dc.subject.otherGenetics
dc.titleEvidence of association of the NLRP1 gene with giant cell arteritis
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion

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