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Data on the effect of early treatment with ivermectin on viral load, symptoms and humoral response in patients with mild COVID-19
(2021-01) Chaccour, Carlos; Casellas, Aina; Blanco-Di Matteo, Andrés; Pineda, Iñigo; Fernández Montero, Alejandro; Ruiz Castillo, Paula; Richardson, Mary-Ann; Rodríguez Mateos, Mariano; Jordán Iborra, Carlota; Brew, Joe; Carmona Torre, Francisco; Giráldez, Miriam; Laso, Ester; Dobaño, Carlota, 1969-; Moncunill Piñas, Gemma; Yuste, José R.; Pozo, José Luis del; Rabinovich, Regina; Schöning, Verena; Hammann, Felix; Reina, Gabriel; Sadaba, Belen; Fernández Alonso, Miriam
The trial was conducted in the Pamplona metropolitan area (Navarra, Spain). Patients were enrolled between July 31, 2020 and September 11, 2020 and randomized in a 1:1 ratio to ivermectin (400 mcg/kg) single oral dose or placebo. Assessments on enrollment and at days 4, 7, 14, 21 and 28 post treatment included: general symptoms report, physical examination and adverse events. All patients were asked to complete a daily online diary of symptoms from day 1 to 28 post treatment. On enrollment, as well as on days 7 and 14 blood samples were obtained to assess full blood count, C reactive protein, procalcitonin, ferritin, creatinine phosphokinase, lactic dehydrogenase, troponin T, D dimer, IL-6, and renal function. Viral loads were calculated at enrollment and on days 4, 7, 14 and 21 post treatment based on a nasopharyngeal swab for SARS-CoV-2 PCR (for genes N and E). A semi-quantitative serology for IgG against SARS-CoV-2 was done on samples from all patients on day 21 post-treatment.
Bulwer's petrel Capture-Mark-Recapture data
(2021-01-04) Cruz Flores, Marta; Pradel, Roger; Bried, Joël; González-Solís, Jacob; Ramos i Garcia, Raül
Bulwer’s petrel captures from 2007 to 2018 specifying the reproductive performance/status of the individuals (1=unknown reproductive performance, 2=successful breeder, 3=failure at incubation, 4=failure at chick-rearing, 5=non-breeder and 6=breeder with unknown reproductive performance), their colony (Vila or Montaña Clara) and their sex (0=not sexed, 1=male and 2=female). Data from Vila islet in Azores Islands were collected from 2007 to 2012 and in 2016; data from Montaña Clara islet in Canary Islands were collected from 2010 to 2018.
Expression and splicing quantitative trait locus (e/sQTLs) summary statistics from normal colon tissue
(2020-12) Diez Obrero, Virginia; Dampier, Christopher H.; Moratalla Navarro, Ferran; Devall, Matthew; Plummer, Sarah J.; Díez Villanueva, Anna; Peters, Ulrike; Bien, Stephanie A.; Huyghe, Jeroen R.; Kundaje, Anshul; Ibáñez Sanz, Gemma; Guinó, Elisabet; Obón Santacana, Mireia; Carreras Torres, Robert; Casey, Graham; Moreno Aguado, Víctor
We profiled gene expression and alternative splicing of non-neoplastic colon from biopsies of 445 healthy individuals. Here we provide summary statistics listings of BarcUVa-Seq eQTLs and sQTLs (from SUPPA2 and from LeafCutter), and of GTEx v8 transverse colon and sigmoid colon sQLTs (from SUPPA2). Filenames indicate the content of each file: {study}.{analysis}.{method}.
Sexual segregation in the foraging behaviour of a slightly dimorphic seabird: influence of the environment and fishery activity (Raw data)
(2020-11) Reyes-González, José Manuel; Felipe, Fernanda de; Morera Pujol, Virginia; Soriano Redondo, Andrea; Navarro Herrero, Leia; Zango, Laura; García Barcelona, Salvador; Ramos i Garcia, Raül; González-Solís, Jacob
Dades d'isòtops estables referents a la recollida de sang (plasma) de l'espècie Scopoli's shearwater Calonectris diomedea, durant l'època de cría dels anys 2012, 2014, 2014 i 2015 a la colònia de Cala Morell, Menorca, Illes Balears
University students’ motives-for-physical-activity profiles: why they practise and what they get in terms of psychological need satisfaction (Raw data)
(2020-10) Valenzuela, Rafael; Codina, Núria (Codina Mata); Pestana, José Vicente
Raw data from a study about understanding university students’ motives for physical activity (PA), and their relationships with Psychological Need Satisfaction (PNS) and characteristics of practice regularity (frequency, duration, team, competitive, coach, league, federation, and type of day of the week for PA).
Effects of high-intensity training and a high-protein diet on body composition, muscle metabolism and muscle strength in overweight adults: a systematic review and meta-analysis
(2020-10) Gervilla Barbero, Sandra; Beltrán Garrido, José Vicente; Farran, Andreu
The increase in high-intensity training (HIT) guidelines and the use of hyperproteic diets (HPDs) as a treatment of excess weight in adults have generated interest in their effects on body composition, metabolic profile and muscular strength. So, the objective of this study was to determine the effects of HIT together with an HPD on the body composition, muscle metabolism and muscle strength of overweight or obese subjects. According to that, a standardized search of randomized controlled trials was carried out considering: 1) application of a HIT protocol, 2) compliance with an HPD and 3) their combined application in non-active overweight or obese subjects. Screening was then carried out by two independent researchers, following the criteria in the Cochrane handbook for systematic reviews of interventions. Data was extracted from the 8 studies selected which were systematically reviewed, and subsequent meta-analysis was performed. A statistically significant decrease in body fat (6 studies which included n=294 subjects; MD -0.56 kg; 95% CI -0.90 to -0.22 kg; p=0.001; I2 =18%; Chi2=6.08; p=0.30) and an increase in lean body mass (7 studies which included n=370 subjects; MD 0.37 kg; 95% CI 0.02 to 0.72 kg; p=0.04; I2 =55%; Chi2=13.42; p=0.04) were detected. Sensitivity analysis confirmed the significance of these results. No statistically significant changes were observed in any of the other variables studied. Despite the statistically significant decrease in body fat and increase in lean body mass, not statistically or clinically significant improvements were observed in the other variables, not even in those where favorable changes had been reported in previous studies. For obtaining more conclusive results in future meta-analysis, it will be necessary to carry out new studies with less variable and better-defined HIT and HPD protocols in order to increase comparability. These studies should control subjects’ diet conveniently, especially protein and energy intake.
Functioning in adult patients with idiopathic inflammatory myopathy: Exploring the role of environmental factors using focus groups (Raw Data)
(2020-10-02) Armadans Tremolosa, Immaculada; Guilera Ferré, Georgina; Heras, Marta Las; Castrechini Trotta, Ángela; Selva O'Callaghan, Albert
Raw data from the study “Functioning in adult patients with idiopathic inflammatory myopathy: Exploring the role of environmental factors using focus groups”. The document shows that the most ICF categories cited by the patients were related to products or substances for personal consumption (e110), such as medication and disease-related healthy food issues in the diet, the importance of the relationship with health professionals (e355), including doctors, nurses, psychologists, and physiotherapists, accessibility to health services (e580), technological support (e115), the role of caregivers (e310), and certain problems related with the disability caused by the disease, such as muscle weakness, intolerance to physical activity, and fatigue, with their consequences on mobility. The ICF categories related to environmental factors identified here are of value for clinicians treating patients with these rare diseases, as they raise awareness of the need to reinforce the facilitating role of specific environmental factors and reduce the negative impact of others to improve the patients’ daily functioning.
ERC Artsoundscapes project – rough data related to the Facebook page
(2020-08) Coltofean, Laura; Díaz-Andreu, Margarita; Mattioli, Tommaso
Datos recogidos en el marco del proyecto de la ERC "The sound of special places: exploring rock art soundscapes and the sacred" (acrónimo: Artsoundscapes) que tiene como Investigadora Principal la ICREA Research Professor Margarita Díaz-Andreu centrado en el campo de la arqueoacústica y el arte rupestre. En el artículo se analiza el potencial de los medios de comunicación social en general y de Facebook en particular para difundir y comunicar los conocimientos arqueológicos y las formas en que se puede mejorar su impacto en el público inspirándose en planes de comercialización desarrollados para el mundo de la empresa. Utilizando datos cuantitativos y cualitativos proporcionados por la herramienta de altmetría Facebook Insights, el artículo evalúa el impacto de la página Artsoundscapes y mide la eficacia del plan de comercialización, examinando los diferentes componentes de estos planes y haciendo hincapié en la estrategia de contenido que se ha seguido y que fue cuidadosamente diseñada al principio del proyecto y que ha conseguido que en tan sólo 19 meses de existencia haya desarrollado una activa comunidad en línea de 757 fans y 787 seguidores de 45 países.
An integrated account of expert perspectives on functioning in schizophrenia (Raw Data)
(2020-07-30) Nuño Gómez, Laura, 1967-; Guilera Ferré, Georgina; Rojo Rodés, José Emilio; Gómez Benito, Juana; Barrios Cerrejón, M. Teresa
Raw data from the study “an integrated account of expert perspectives on functioning in schizophrenia”. The document shows individual responses to the last round of the study. the study aims to evaluate the content validity of the ICF-CSs for schizophrenia from the perspective of experts in the treatment of this population, as well as to identify the potential repercussions of this health condition in the functioning of people diagnosed with this disorder. The results provide important support for the worldwide content validity of the ICF-CSs for schizophrenia from the expert perspective and highlight the relevance, in the evaluation and treatment of people with schizophrenia, of assessing functioning by considering the body functions, participation in activities, environmental aspects and personal factors that experts have identified.
Antibody responses to the RTS,S/AS01E vaccine and Plasmodium falciparum antigens after a booster dose within the phase 3 trial in Mozambique (Raw Data)
(2020-05) Dobaño, Carlota, 1969-; Sánchez, Lina; Vidal, Marta; Jairoce, Chenjerai Tobias Sixpence; Aguilar, Ruth; Ubillos, Itziar; Cuamba, Inocencia; Nhabomba, Augusto J.; Williams, Nana Aba; Diez-Padrisa, Núria; Cavanagh, David; Angov, Evelina; Coppel, Ross L.; Gaur, Deepak; Beeson, James G.; Dutta, Sheetij; Aide, Pedro Carlos Paulino; Campo, Joseph J.; Moncunill Piñas, Gemma
The RTS,S/AS01E vaccine has shown consistent but partial vaccine efficacy in a pediatric phase 3 26 clinical trial using a 3-dose immunization schedule. A fourth dose 18 months after the primary 27 vaccination was shown to restore the waning efficacy. However, only total IgG against the 28 immunodominant malaria vaccine epitope has been analyzed following the booster. To better 29 characterize the magnitude, nature and longevity of the immune response to the booster, we 30 measured levels of total IgM, IgG and IgG1-4 subclasses against three constructs of the 31 circumsporozoite protein (CSP) and the hepatitis B surface antigen (HBsAg, also present in RTS,S) 32 by quantitative suspension array technology in 50 subjects in the phase 3 trial in Manhiça, 33 Mozambique. To explore the impact of vaccination on naturally acquired immune responses, we 34 measured antibodies to P. falciparum antigens not included in RTS,S. We found increased IgG, 35 IgG1, IgG3 and IgG4, but not IgG2 nor IgM, levels against vaccine antigens one month after the 4th 36 dose. Overall, antibody responses to the booster dose were lower than the initial peak 37 response to primary immunization and children had higher IgG and IgG1 levels than infants. 38 Higher anti-Rh5 IgG and IgG1-4 levels were detected after the booster dose, suggesting that RTS,S 39 partial protection could increase some blood stage antibody responses. Our work shows that the 40 response to the RTS,S/AS01E booster dose is different from the primary vaccine immune 41 response and highlights the dynamic changes in subclass antibody patterns upon the vaccine 42 booster and with acquisition of adaptive immunity to malaria.
Dataset from Effectiveness of Consumers Washing with Sanitizers to Reduce Human Norovirus on Mixed Salad
(2020-06-02) Anfruns-Estrada, Eduard; Bottaro, Marilisa; Pintó Solé, Rosa María; Guix Arnau, Susana; Bosch, Albert
Viral titers were collected following a method based on the ISO 15216-1 (2017) protocol with some modifications, on experimentally inoculated ready-to-eat vegetables. See Materials and Methods section of the manuscript. Effect of the sanitizer wash on virus reduction was determined by calculating the log units (Nt/N0), where N0 is the titer of virus recovered on unwashed control samples and Nt is the titer of virus recovered on washed sample.
Dataset containing data used in the study “Long-term farming systems and last crop sown shape the species and functional composition of the arable weed seedbank”
(2020-04) Rotchés Ribalta, Roser; Sans, Xavier (Sans i Serra); Mäder, Paul
Species diversity descriptors (abundance, species richnnes, Shannon’s diversity index and Pielou’s evenness index) and functional diversity descriptors (functional richness, functional evenness, functional dispersion, Rao Quadratic enthropy and functional redundancy) for each sample inventoried from the DOK long-term experimental field trial used by Rotchés-Ribalta et al. (Applied Vegetation Science)
Total Ion Chromatograms obtained by SPME-GC-MS of volatile fingerprint of olive oil samples
(2020-03-25) Quintanilla-Casas, Beatriz; Bustamante Alonso, Julen; Guardiola Ibarz, Francesc; García-González, Diego Luis; Barbier, Sara; Bendini, Alessandra; Gallina Toschi, Tullia; Vichi, S. (Stefania); Tres Oliver, Alba
Dataset containing SPME-GC-MS raw analytical data (total ion chromatograms, not aligned) obtained and used by Quintanilla-Casas et al. (LWT - Food Science and Technology 121: 108936). Data correspond to the volatile fingerprint of 174 authentic and traceable virgin olive oil samples previously graded by six official sensory panels (data from 2 outlier samples are not included) in the framework of OLEUM project (EC H2020 Programme 2014–2020). Briefly, data correspond to SPME-GC-MS scan intensities of the total ion chromatogram at each retention time from 5.5 to 61.96 min. These data were aligned and used under a fingerprinting approach by Quintanilla-Casas et al. to develop a classification model (PLS-DA approach) to verify the sensory quality of virgin olive oils, and it was suggested as an instrumental method to support sensory panels.
SPME-GC-MS raw data for the development of profiling and fingerprinting analysis of sesquiterpene hydrocarbons for the geographical authentication of extra virgin olive oils
(2020-03-24) Quintanilla-Casas, Beatriz; Bertin, Sofia; Leik, Kerstin; Bustamante Alonso, Julen; Guardiola Ibarz, Francesc; Valli, Enrico; Bendini, Alessandra; Gallina Toschi, Tullia; Tres Oliver, Alba; Vichi, S. (Stefania)
Data base containing SPME-GC-MS raw analytical data obtained and used by Quintanilla-Casas et al. (Food Chemistry, 2020, 125556). Data correspond to 82 authentic and traceable olive oil samples, declared as EVOO by the suppliers obtained in the framework of OLEUM project (EC H2020 Programme 2014–2020) from seven different EU and non-EU countries: Croatia (n=11); Slovenia (SVN) (n=8); Spain (ESP) (n=17); Italy (ITA) (n=15); Greece (GRC) (n=6); Morocco (MAR) (n=15) and Turkey (TUR) (n=10). With the aim of reflecting the real production scenario, EVOO samples in this prospective study were obtained under usual production practices for commercial purposes, and thus consisted of both monovarietal oils as well as market blends of olive cultivars typical of each geographical origin. Briefly, data correspond to SPME-GC-MS scan intensities of the specific sesquiterpene hydrocarbon (SH) ions (m/z 93, 107, 119, 135, 157, 159, 161, 189 and 204) obtained from the Total Ion Current (TIC) between the 18th to the 30th minute. Thus, 2467 scans were obtained for each m/z ion implying 22203 variables per sample.
Stable oxygen isotopes reveal habitat use by marine mammals in the Río de la Plata estuary and adjoining Atlantic Ocean (Raw data)
(2020-03-09) Drago, Massimiliano; Valdivia, Meica; Bragg, Daniel; González, Enrique M.; Aguilar, Àlex; Cardona Pascual, Luis
The bone stable oxygen isotope values and the distance of the stranding site from the innermost point of the estuary for thirteen marine mammal species (Otaria flavescens, Arctocephalus australis, Pontoporia blainvillei, Ziphius cavirostris, Phocoena dioptrica, Phocoena spinipinnis, Delphinus delphis, Globicephala melas, Grampus griseus, Lagenodelphis hosei, Orcinus orca, Pseudorca crassidens and Tursiops truncatus) from the Río de la Plata estuary and the adjoining western South Atlantic Ocean. Stable oxygen isotope values (δ18O) are reported relative to the Vienna Standard Mean Oceanic Water (V-SMOW).
Cytokine signatures of Plasmodium vivax infection during pregnancy and delivery outcomes (Raw Data)
(2020-03-02) Dobaño, Carlota, 1969-; Bardají, Azucena; Arévalo Herrera, Myriam; Martínez Espinosa, Flor E.; Botto Menezes, Camila; Padilla, Norma; Menegon, Michela; Kochar, Swati; Kochar, Sanjay K.; Unger, Holger Werner; Ome-Kaius, Maria; Rosanas Urgell, Anna; Malheiros, Adriana; Castellanos, Maria Eugenia; Hans, Dhiraj; Desai, Meghna; Casellas, Aina; Chitnis, Chetan E.; Severini, Carlo; Mueller, Ivo; Rogerson, Stephen John; Menéndez, Clara; Requena, Pilar
Plasmodium vivax malaria is a neglected disease, particularly during pregnancy. Severe vivax malaria is associated with inflammatory responses but in pregnancy immune alterations make it uncertain as to what cytokine signatures predominate, and how the type and quantity of blood immune mediators influence delivery outcomes. We measured the plasma concentrations of a set of thirty-one biomarkers, comprising cytokines, chemokines and growth factors, in 987 plasma samples from a cohort of 572 pregnant women from five malaria-endemic tropical countries and related these concentrations to delivery outcomes (birth weight and hemoglobin levels) and malaria infection. Samples were collected at recruitment (first antenatal visit) and delivery (periphery, cord and placenta), allowing a longitudinal analysis. At recruitment, we found that P. vivax–infected pregnant women had higher plasma concentrations of proinflammatory (IL-6, IL-1β, CCL4, CCL2, CXCL10) and TH1-related cytokines (mainly IL-12) than uninfected women. This biomarker signature was essentially lost at delivery and was not associated with birth weight nor hemoglobin levels. Antiinflammatory cytokines (IL-10) were positively associated with infection and poor delivery outcomes. CCL11 was the only biomarker to show a negative association with P. vivax infection and its concentration at recruitment was positively associated with hemoglobin levels at delivery. Birth weight was negatively associated with peripheral IL-4 levels at delivery. Our multi-biomarker multicenter study is the first comprehensive one to characterize the immunological signature of P. vivax infection in pregnancy thus far. In conclusion, data show that while TH1 and pro-inflammatory responses are dominant during P. vivax infection in pregnancy, antiinflammatory cytokines may compensate excessive inflammation avoiding poor delivery outcomes, and skewness toward a TH2 response may trigger worse delivery outcomes. CCL11, a chemokine largely neglected in the field of malaria, emerges as an important marker of exposure or mediator in this condition.
Gender-differences in conservatoire music practice maladjustment. Can contextual professional goals and context-derived psychological needs satisfaction account for amotivation variations? [Raw Data]
(2020-02-05) Valenzuela, Rafael; Codina, Núria (Codina Mata); Pestana, José Vicente
Raw data from a study about Gender-differences in music practice, which takes into account contextual goals, psychological needs satisfaction and amotivation. The present study is one of the first to assess gender-differences in amotivation in conservatoire instrument practice, linking these with musicians’ psychological need satisfaction, showing that women musicians may be perceiving the need for autonomy more closely linked with amotivation than their men counterparts.
Mitochondrial toxicogenomics for antiretroviral management: HIV Post-exposure prophylaxis in uninfected patients (Raw Data)
(2019-10-28) Garrabou Tornos, Glòria; Martínez, Esteban
PERCEIVE WP2: Evaluation of EU citizens’ perception of the EU project: Key variables for citizens' identification with EU - Datasets - PART B
(2019-07) Calia, Pinuccia; López-Bazo, Enrique; Moreno Serrano, Rosina; Royuela Mora, Vicente; Suriñach Caralt, Jordi
This dataset refers to PERCEIVE tasks 2.4 and 2.5. These tasks analyze the data sets developed by PERCEIVE task 2.1 in order to identify, quantify and synthetize the most important variables to asses identification with EU by citizens. The results feed an update of the data set developed in task 2.1. Finally, these data is be used to model convergence of EU citizens' identification in the case study regions. Data consists of the quantitative statistical information used to produce all the results of WP2 and the indicators regarding the variables of interest obtained by means of different statistical techniques. Moreover, data on absorption of EU funds, provided by the EC and other research centres and collected in task 2.5, is be gathered in this data set, together with the results of convergence analysis. This data set is be used to evaluate the EU citizens’ perception of the EU project in relation to regional performance of the cohesion policy and institutional quality. WP2 uses primary data from the survey developed in WP1 (“PERCEIVE: WP1: Framework for comparative analysis of the perception of Cohesion Policy and identification with the European Union at citizen level in different European countries: Task1.3: Survey at citizen level” data set) and also comparative case studies on EU countries and regions, coming also from WP1 (”PERCEIVE: WP1: Framework for comparative analysis of the perception of Cohesion Policy and identification with the European Union at citizen level in different European countries: Task1.1: The framework for the comparative analysis” and ”PERCEIVE: WP1: Framework for comparative analysis of the perception of Cohesion Policy and identification with the European Union at citizen level in different European countries: Task1.2: Focus group with Cohesion Policy practitioners” data sets). The data set incorporates data from existing sources including Eurostat and information resulting from the Survey conducted at WP1 of the PERCEIVE’s project. As regards secondary data, no additional treatment is needed. Info about the sources of such data, including references to technical details, is provided in the dataset's codebook.
Executive functions, Personality traits and ADHD symptoms in adolescents: A mediation analysis (Raw data)
(2019-07-25) Krieger, Virginia; Amador, Juan Antonio; Guàrdia-Olmos, Joan, 1958-
Raw data and data analysis scripts from the study “Executive functions, Personality traits and ADHD symptoms in adolescents: A mediation analysis”. This study aimed to analyze the associations between performance on cognitive executive function (EF) measures and FFM personality traits in a sample of adolescents with and without ADHD.

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