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2010

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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/48630

Preparation of alpha-labeled aldehydes by base-catalyzed exchange reactions

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Abstract

A simple, efficient protocol for the preparation of α-labeled aldehydes based on H/D exchange catalyzed by 4-(N,N-dimethylamino)pyridine or Et3N is described. High chemical yields and ratios of isotope incorporation were obtained even when small amounts (1 mmol) of aldehyde were used.

Related resource

http://dx.doi.org/10.1002/jlcr.1759

Subject

Trastorns del metabolisme dels lípids, Bioquímica, Aldehids, Disseny de medicaments, Medicina nuclear

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Lipid metabolism disorders, Biochemistry, Aldehydes, Drug design, Nuclear medicine

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Articles publicats en revistes (Química Inorgànica i Orgànica)
Articles publicats en revistes (Bioquímica i Biomedicina Molecular)

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ARIZA PIQUER, Xavier, et al. Preparation of alpha-labeled aldehydes by base-catalyzed exchange reactions. Journal of Labelled Compounds and Radiopharmaceuticals. 2010. Vol. 53, num. 8, pags. 556-558. ISSN 0362-4803. [consulted: 5 of October of 2026]. Available at: https://hdl.handle.net/2445/48630

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