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Fitxers

619267.pdf (321.66 KB)

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Article

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Data de publicació

2012

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cc-by (c) Oyarzún, J. et al., 2012
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/36389

Updating Farful Memories with Extinction Training during Reconsolidation: A Human Study Using Auditory Aversive Stimuli

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Recurs relacionat

http://dx.doi.org/10.1371/journal.pone.0038849

Resum

Learning to fear danger in the environment is essential to survival, but dysregulation of the fear system is at the core of many anxiety disorders. As a consequence, a great interest has emerged in developing strategies for suppressing fear memories in maladaptive cases. Recent research has focused in the process of reconsolidation where memories become labile after being retrieved. In a behavioral manipulation, Schiller et al., (2010) reported that extinction training, administrated during memory reconsolidation, could erase fear responses. The implications of this study are crucial for the possible treatment of anxiety disorders without the administration of drugs. However, attempts to replicate this effect by other groups have been so far unsuccessful. We sought out to reproduce Schiller et al., (2010) findings in a different fear conditioning paradigm based on auditory aversive stimuli instead of electric shock. Following a within-subject design, participants were conditioned to two different sounds and skin conductance response (SCR) was recorded as a measure of fear. Our results demonstrated that only the conditioned stimulus that was reminded 10 minutes before extinction training did not reinstate a fear response after a reminder trial consisting of the presentation of the unconditioned stimuli. For the first time, we replicated Schiller et al., (2010) behavioral manipulation and extended it to an auditory fear conditioning paradigm.

Matèries

Trastorn per estrès posttraumàtic, Trastorns auditius, Estudi de casos

Matèries (anglès)

Post-traumatic stress disorder, Hearing disorders, Case studies

Citació

Col·leccions

Articles publicats en revistes (Cognició, Desenvolupament i Psicologia de l'Educació)
Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

Citació

OYARZÚN, Javiera P., et al. Updating Farful Memories with Extinction Training during Reconsolidation: A Human Study Using Auditory Aversive Stimuli. PLoS One. 2012. Vol. 7, núm. 6, pàgs. e38849. ISSN 1932-6203. [consulta: 8 de maig de 2026]. Disponible a: https://hdl.handle.net/2445/36389

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