Carregant...
Tipus de document
AltresVersió
Versió acceptadaData de publicació
Tots els drets reservats
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/118182
A role for caspase-8 and TRAIL-R2/DR5 in ER-stress induced apoptosis
Títol de la revista
Director/Tutor
ISSN de la revista
Títol del volum
Recurs relacionat
Resum
Glab and colleagues examine in a recent paper apoptosis induced by some driverss of
endoplasmic reticulum (ER) stress. They conclude that in contrast to a previously published
report2
, DR5/TRAIL-R2 and caspase-8 are universally dispensable in ER stress-induced
apoptosis. We argue here that their own data and other published reports indicate that in
many models, DR5 and/or caspase-8 are essential players in apoptosis mediated by the
unfolded protein response (UPR), upon chronic ER stress.
Citació
Citació
MUÑOZ PINEDO, Cristina, LÓPEZ RIVAS, Abelardo. A role for caspase-8 and TRAIL-R2/DR5 in ER-stress induced apoptosis. _Cell Death & Differentiation_. 2017. Vol. 1 October. [consulta: 9 de febrer de 2026]. ISSN: 1476-5403. [Disponible a: https://hdl.handle.net/2445/118182]