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Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/147198

Immune Exclusion-Wnt/CTNNB1 Class Predicts Resistance to Immunotherapies in HCC

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Next-generation sequencing has provided information on actionable targets and biomarkers of response in oncology. In hepatocellular carcinoma (HCC), Wnt/CTNNB1 mutations characterize the immune-excluded class (cold tumors) and might represent the biomarkers predicting resistance to immune checkpoint inhibitors. Large-scale validation of these data is needed to customize immunotherapy in advanced HCC.See related article by Harding et al.©2019 American Association for Cancer Research.

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PINYOL, Roser, SIA, Daniela and LLOVET I BAYER, Josep Maria. Immune Exclusion-Wnt/CTNNB1 Class Predicts Resistance to Immunotherapies in HCC. Clinical Cancer Research. 2019. Vol. 25, num. 7, pags. 2021-2023. ISSN 1078-0432. [consulted: 25 of May of 2026]. Available at: https://hdl.handle.net/2445/147198

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